Diabetes Related to Schizophrenia

Wed, 09 Jun 2010
Reseachers state that problems in insulin function characteristic in diabetes and obesity may directly contribute to psychiatric disorders, such as, schizophrenia.

Vanderbilt University Medical Center researchers have uncovered a molecular link between impaired insulin signalling in the brain and schizophrenia type behaviors in mice.

These findings provide a fresh perspective on the psychiatric and cognitive disorders which affect patients with diabetes and suggest new strategies for treatment of these conditions.

Diabetics can be more prone to mood swings and other psychiatric disorders.

This is one of the reasons why diabetics have problems managing their diabetes.

Something malfunctions in the brain as insulin is not signaling the way it usually does.

Insulin, the hormone which governs the body's glucose metabolism, also regulates the brain's supply of dopamine, a neurotransmitter with roles in terms of motor activity, reward and attention.

Interrupted dopamine signalling has been linked to brain disorders like depression, schizophrenia, Parkinson's disease and attention-deficit hyperactivity disorder.

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