Bones Play A Big Part in Diabetes

Fri, 23 Jul 2010
Two new studies have studied the interplay between bone and blood sugar, suggesting that bones play a more significant role with regard to the onset of diabetes than previously considered.

The bones of mice cannot respond to insulin; they develop high blood sugar and insulin resistance, which are both signs of diabetes, so researchers have found.

Those symptoms are related to a decrease in a bone-derived hormone called osteocalcin.

The findings suggest that osteocalcin, or perhaps a drug that targets bone, might hold promise in fighting the global epidemic of type 2 diabetes, according to the researchers.

The study shows a main molecular relation between bone remodeling and metabolism .

Obese adults are significantly less likely to develop osteoporosis.

Those with type 1 diabetes are susceptible to weakened bones due to a lack of insulin .

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